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human pca cell line c4 2b  (ATCC)


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    ATCC human pca cell line c4 2b
    Human Pca Cell Line C4 2b, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 628 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+pca+cell+lines+c4+2b/C4-2B/pm41702447-51-8-17
    Average 97 stars, based on 628 article reviews
    human pca cell line c4 2b - by Bioz Stars, 2026-10
    97/100 stars

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    Related Articles

    Modification:

    Article Title: ZNF711 promotes enzalutamide resistance through transcriptional and epigenetic modification of the androgen receptor signaling pathway.
    Article Snippet: .. Human PCa cell lines C4-2B, LNCaP (RRID: CVCL_0395), 22Rv1 (RRID: CVCL_1045), and HEK 293 T (RRID: 1 3 103 Page 2 of 17 ZNF711 promotes enzalutamide resistance through transcriptional and epigenetic modification of the... CVCL_0063) were obtained from the American Type Culture Collection (ATCC, Rockville, MD, USA) and cultured following ATCC’s instructions. ..

    Cell Culture:

    Article Title: ZNF711 promotes enzalutamide resistance through transcriptional and epigenetic modification of the androgen receptor signaling pathway.
    Article Snippet: .. Human PCa cell lines C4-2B, LNCaP (RRID: CVCL_0395), 22Rv1 (RRID: CVCL_1045), and HEK 293 T (RRID: 1 3 103 Page 2 of 17 ZNF711 promotes enzalutamide resistance through transcriptional and epigenetic modification of the... CVCL_0063) were obtained from the American Type Culture Collection (ATCC, Rockville, MD, USA) and cultured following ATCC’s instructions. ..

    Article Title: ZNF711 promotes enzalutamide resistance through transcriptional and epigenetic modification of the androgen receptor signaling pathway
    Article Snippet: .. Human PCa cell lines C4-2B, LNCaP (RRID: CVCL_0395), 22Rv1 (RRID: CVCL_1045), and HEK 293 T (RRID: CVCL_0063) were obtained from the American Type Culture Collection (ATCC, Rockville, MD, USA) and cultured following ATCC’s instructions. ..

    Article Title: Tumor removal limits prostate cancer cell dissemination in bone and osteoblasts induce cancer cell dormancy through focal adhesion kinase
    Article Snippet: Murine Osteocyte-like Cell Line MLO-Y4 were grown in α-MEM supplemented with 5% FBS and 5% calf serum (CS) on the plate pre-coated with rat tail type 1 collagen (0.15 mg/mL, Corning, Corning, NY). .. Human PCa cell lines C4-2B (gift from Dr. Leland Chung and purchased from ATCC), PC-3, DU-145, and 22Rv1 were cultured in RPMI-1640 supplemented with 10% FBS. ..

    Article Title: Tumor removal limits prostate cancer cell dissemination in bone and osteoblasts induce cancer cell dormancy through focal adhesion kinase.
    Article Snippet: Murine Osteocyte-like Cell Line MLO-Y4 were grown in α-MEM supplemented with 5% FBS and 5% calf serum (CS) on the plate pre-coated with rat tail type 1 collagen (0.15 mg/ mL, Corning, Corning, NY). .. Human PCa cell lines C4-2B (gift from Dr. Leland Chung and purchased from ATCC), PC-3, DU-145, and 22Rv1 were cultured in RPMI-1640 supplemented with 10% FBS. ..

    Multiple Displacement Amplification:

    Article Title: Exosomes-Mediated Transfer of Itga2 Promotes Migration and Invasion of Prostate Cancer Cells by Inducing Epithelial-Mesenchymal Transition
    Article Snippet: .. The human PCa cell lines C4-2B, DU145, PC-3, LNCaP, MDA-PCa-2b, and normal prostate RWPE-1 cells were purchased from American Type Culture Collection (ATCC, Manassas, VA, USA). .. CWR-R1ca cells were purchased from Millipore Sigma (Burlington, MA, USA).



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    human pca cell line c4 2b  (ATCC)
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    ATCC human pca cell line c4 2b
    Human Pca Cell Line C4 2b, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+pca+cell+lines+c4+2b/C4-2B/pm41702447-51-8-17
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    human pca cell lines c4 2b  (ATCC)
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    human pca cell lines  (ATCC)
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    UFL1 is downregulated in ENZR CRPC. (A) Analysis of UFL1 level in <t>human</t> <t>PCa</t> samples from the TCGA-PRAD dataset. (B) Representative IHC staining images for UFL1 in PCa tissues. (C) Statistical analysis of UFL1 protein levels by IHC. (D) WB examination demonstrating UFL1 protein levels in fresh PCa tumors and paired normal tissues. (E-H) Correlation of UFL1 mRNA level with Gleason score (E), clinical stage (F), lymph node metastasis (G), and distant metastasis (H). (I-J) UFL1 levels in PCa <t>cell</t> <t>lines.</t> LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were procured and examined by qRT-PCR (I) and WB (J). (K) Representative IHC images of UFL1 staining in tumor sections from xenograft mice. (L) UFL1 expression in the public GSE44927 dataset. (M-N) Representative IHC images demonstrating UFL1 level in CSPC and CRPC tissues. (O) Examination of UFL1 expression in human PCa samples from GEO datasets. (P-Q) In the published PCa cohort ( GSE116918 ) and TCGA-PRAD dataset, reduced UFL1 expression was correlated with worse overall survival. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.
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    reagents472 human pca cell lines  (ATCC)
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    ATCC reagents472 human pca cell lines
    UFL1 is downregulated in ENZR CRPC. (A) Analysis of UFL1 level in <t>human</t> <t>PCa</t> samples from the TCGA-PRAD dataset. (B) Representative IHC staining images for UFL1 in PCa tissues. (C) Statistical analysis of UFL1 protein levels by IHC. (D) WB examination demonstrating UFL1 protein levels in fresh PCa tumors and paired normal tissues. (E-H) Correlation of UFL1 mRNA level with Gleason score (E), clinical stage (F), lymph node metastasis (G), and distant metastasis (H). (I-J) UFL1 levels in PCa <t>cell</t> <t>lines.</t> LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were procured and examined by qRT-PCR (I) and WB (J). (K) Representative IHC images of UFL1 staining in tumor sections from xenograft mice. (L) UFL1 expression in the public GSE44927 dataset. (M-N) Representative IHC images demonstrating UFL1 level in CSPC and CRPC tissues. (O) Examination of UFL1 expression in human PCa samples from GEO datasets. (P-Q) In the published PCa cohort ( GSE116918 ) and TCGA-PRAD dataset, reduced UFL1 expression was correlated with worse overall survival. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.
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    Image Search Results


    UFL1 is downregulated in ENZR CRPC. (A) Analysis of UFL1 level in human PCa samples from the TCGA-PRAD dataset. (B) Representative IHC staining images for UFL1 in PCa tissues. (C) Statistical analysis of UFL1 protein levels by IHC. (D) WB examination demonstrating UFL1 protein levels in fresh PCa tumors and paired normal tissues. (E-H) Correlation of UFL1 mRNA level with Gleason score (E), clinical stage (F), lymph node metastasis (G), and distant metastasis (H). (I-J) UFL1 levels in PCa cell lines. LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were procured and examined by qRT-PCR (I) and WB (J). (K) Representative IHC images of UFL1 staining in tumor sections from xenograft mice. (L) UFL1 expression in the public GSE44927 dataset. (M-N) Representative IHC images demonstrating UFL1 level in CSPC and CRPC tissues. (O) Examination of UFL1 expression in human PCa samples from GEO datasets. (P-Q) In the published PCa cohort ( GSE116918 ) and TCGA-PRAD dataset, reduced UFL1 expression was correlated with worse overall survival. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Journal: International Journal of Biological Sciences

    Article Title: Loss of UFL1 confers enzalutamide resistance of prostate tumors by regulating METTL16-mediated m6A modification of EEF1A1 mRNA

    doi: 10.7150/ijbs.124214

    Figure Lengend Snippet: UFL1 is downregulated in ENZR CRPC. (A) Analysis of UFL1 level in human PCa samples from the TCGA-PRAD dataset. (B) Representative IHC staining images for UFL1 in PCa tissues. (C) Statistical analysis of UFL1 protein levels by IHC. (D) WB examination demonstrating UFL1 protein levels in fresh PCa tumors and paired normal tissues. (E-H) Correlation of UFL1 mRNA level with Gleason score (E), clinical stage (F), lymph node metastasis (G), and distant metastasis (H). (I-J) UFL1 levels in PCa cell lines. LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were procured and examined by qRT-PCR (I) and WB (J). (K) Representative IHC images of UFL1 staining in tumor sections from xenograft mice. (L) UFL1 expression in the public GSE44927 dataset. (M-N) Representative IHC images demonstrating UFL1 level in CSPC and CRPC tissues. (O) Examination of UFL1 expression in human PCa samples from GEO datasets. (P-Q) In the published PCa cohort ( GSE116918 ) and TCGA-PRAD dataset, reduced UFL1 expression was correlated with worse overall survival. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Article Snippet: Human PCa cell lines (LNCaP and C4-2B) along with HEK293T cells were procured from the American Type Culture Collection (ATCC) and cultured per the supplier's protocols.

    Techniques: Immunohistochemistry, Quantitative RT-PCR, Staining, Expressing

    METTL16 facilitates PCa cell growth, survival, and ENZR. (A) Violin plots illustrating CERES scores for all METTL family members across 11 PCa cell lines. (B) Analysis of METTL16 expression in human PCa samples from GEO datasets. (C) Representative IHC staining images for METTL16 and a statistical graph of METTL16 protein levels. (D) METTL16 expression in PCa cell lines. LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were collected, and total lysates were analyzed by WB (D). (E-J) Cell proliferation assessment utilized CCK-8 assay and colony formation assay in LNCaP-ENZR and C4-2B-ENZR cells following transfection with siNC or METTL16 siRNA. (K-L) Cell viability determination occurred in the designated cell lines during ENZ treatment. LNCaP-ENZR and C4-2B-ENZR cells underwent transfection as specified and received graded ENZ doses over 3 days. Cell viability quantification employed CCK-8 assays. (M-N) Recovery effects of wild-type METTL16 and catalytically inactive METTL16 mutants on METTL16 knockdown-mediated cell proliferation inhibition in LNCaP-ENZR and C4-2B-ENZR cells. (O-P) Cell viability determination in specified cell lines under ENZ treatment. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Journal: International Journal of Biological Sciences

    Article Title: Loss of UFL1 confers enzalutamide resistance of prostate tumors by regulating METTL16-mediated m6A modification of EEF1A1 mRNA

    doi: 10.7150/ijbs.124214

    Figure Lengend Snippet: METTL16 facilitates PCa cell growth, survival, and ENZR. (A) Violin plots illustrating CERES scores for all METTL family members across 11 PCa cell lines. (B) Analysis of METTL16 expression in human PCa samples from GEO datasets. (C) Representative IHC staining images for METTL16 and a statistical graph of METTL16 protein levels. (D) METTL16 expression in PCa cell lines. LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were collected, and total lysates were analyzed by WB (D). (E-J) Cell proliferation assessment utilized CCK-8 assay and colony formation assay in LNCaP-ENZR and C4-2B-ENZR cells following transfection with siNC or METTL16 siRNA. (K-L) Cell viability determination occurred in the designated cell lines during ENZ treatment. LNCaP-ENZR and C4-2B-ENZR cells underwent transfection as specified and received graded ENZ doses over 3 days. Cell viability quantification employed CCK-8 assays. (M-N) Recovery effects of wild-type METTL16 and catalytically inactive METTL16 mutants on METTL16 knockdown-mediated cell proliferation inhibition in LNCaP-ENZR and C4-2B-ENZR cells. (O-P) Cell viability determination in specified cell lines under ENZ treatment. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Article Snippet: Human PCa cell lines (LNCaP and C4-2B) along with HEK293T cells were procured from the American Type Culture Collection (ATCC) and cultured per the supplier's protocols.

    Techniques: Expressing, Immunohistochemistry, CCK-8 Assay, Colony Assay, Transfection, Knockdown, Inhibition